Leva Medical Blogs

Activin Antagonists: The Future of Fat Loss and Muscle Gain Without Diet or Exercise

Written by Dr. Jean-Paul Leva | Oct 5, 2025 4:24:58 PM

Introduction

At Leva Medical in Queens, NY, we constantly explore cutting-edge science shaping the future of weight management and body composition.

One of the most exciting new areas in research is activin antagonists—a class of biologic drugs that could help people burn fat and build muscle simultaneously, even without traditional diet or exercise interventions.

In this article, we’ll break down how these medications work, the results seen in early trials, potential side effects, and how they may complement existing treatments like semaglutide (Ozempic®) or tirzepatide (Mounjaro®) in the coming years.