Leva Medical Blogs

The ‘Fat-Loss Shot Stack’ That Could Replace Ozempic®: Retatrutide + Cagrilintide Explained

Written by Dr. Jean-Paul Leva | Oct 26, 2025 2:11:42 PM

If you thought Ozempic® was the endgame for medical weight loss, think again.
Pharma giants are now developing a dual-hormone stack so potent it’s being called the “Fat-Loss Shot Stack.”

At Leva Medical in Queens, NY, patients often ask about the newest generation of GLP-based therapies, and two names keep coming up: Retatrutide weight loss and Cagrilintide fat loss.

In this article, we’ll break down:

  • What each drug does

  • Why stacking them could accelerate results

  • How they compare to Ozempic vs Retatrutide

  • What’s next for this next-generation treatment